DPCstruct | MC5643

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)173 ± 21 aa
Standard deviation of domain lengths21.01
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score90.47
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)26.14
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U6MK11 967-1166 LRNHPFFRLPRLQPGVKVQQFCVTSAFAFPNMIRHPSQTLGYMRTALAGDTLGESEANGVVLAAQRAVSHLLHFHQEEVPEKRVANA…
U6GS66 3-164 RISRILKKPVVDSGDLRRLMQDLETLVDYAEHCAIENLDGLPPRYVAEKLGFAFLMMDGIYAATEVLGAKARRSEWWQQVIDRLPVY…
U6JUW3 248-436 None
U6JWF8 119-287 None
U6JWK5 141-303 None
U6K1Z7 441-627 None
U6K6R1 93-244 None
U6K4X1 42-245 None
U6JTW8 182-344 None
U6KFB8 2-176 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.