DPCstruct | MC56421

Metacluster Properties and Pfam Annotations

Number of structural domains114
Mean domain length (aa)273 ± 58 aa
Standard deviation of domain lengths58.32
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score90.70
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)19.65
Pfam Score84.61
Assigned Pfam label(s) CL0344- PF04422- PF04432

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C3AWA6 557-858 VEEAQFGIYRSLYAGHALDTDIRKAGVAGGVVTALLAYGLESGALDCAIVAGWDETEPWKVAPKIATTRQELIDCSRSKYSISQTLS…
A0A452Z099 8-218 EPVVHGRGRKDTMDEMYYGVHEQLLYARKMEPVQGAQWTGIVTTIAVEMLKSNMVDAVVCVQSDPDDRFAPRPVLARTPEEVIAARG…
A0A832B2T9 8-194 None
W0ERN0 63-315 None
A0A5C8EIC2 2-263 None
N0BKY2 227-506 None
A0A257MSE1 170-473 None
A0A448Y3F7 598-993 None
A0A3R6QY04 56-371 None
A0A7X3MES7 44-376 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.