DPCstruct | MC56351

Metacluster Properties and Pfam Annotations

Number of structural domains181
Mean domain length (aa)131 ± 25 aa
Standard deviation of domain lengths24.53
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.71
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)27.56
Pfam Score99.59
Assigned Pfam label(s) CL0629- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q7N097 14-144 LPEARSSLLNLKSMVEGITGRNAILSFVGYGCYCGLGGHGLPMDEVDWCCHAHDCCYQKLFDLGCHPYVDHYEHTIENNTSVICSEL…
A0A8B6BL73 22-160 EGLRVKRDLFQLAEMIVDATGRDPLNFNGYGCYCGWGGSGTPVDKDDRCCQQHDDCYGQVTTDLPDCSPKWNHYAWKIQDKTVDCLD…
A0A803KFH5 53-185 None
A0A1S3J4P2 15-100 None
A0A1S3IAI9 197-325 None
E4Y8M7 57-208 None
H0ZT62 102-243 None
A0A2R9B0B2 73-205 None
A0A6J0C6E6 88-209 None
A0A818TTW7 28-172 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.