DPCstruct | MC56348

Metacluster Properties and Pfam Annotations

Number of structural domains486
Mean domain length (aa)141 ± 32 aa
Standard deviation of domain lengths32.19
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score75.81
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.64
Pfam Score68.10
Assigned Pfam label(s) PF05461- CL0236- CL0124- CL0219- PF04434

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A8B6BFQ6 13-157 DLSHLPDISFAFVEEFIRKHSQSSGKEQMTKGFKYYSEEYVHSVSVHPDDTGCLVKGKCFRSQRKNESPHDVKIMLNGVQIEYSFCT…
A0A1J1EHY4 6-105 PEREEDFAPLLPEEVARRGLAYAREGRVRRVFRVGERLLGEVQGSEPTPYRVEVGPGLVGRCTCPYPFFPCKHAAALLYAYLERRPE…
A0A2E8K2H1 31-122 None
A0A7V2T4H9 312-394 None
A0A2N2CAP5 1-109 None
A0A6P8HNX7 111-229 None
A0A2G8LL54 51-255 None
F4KPQ9 5-89 None
A0A7R9A9E8 8-121 None
A0A6G7Y553 1-118 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.