DPCstruct | MC56144

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)71 ± 12 aa
Standard deviation of domain lengths12.21
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score86.29
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)81.51
Pfam Score98.39
Assigned Pfam label(s) PF00223- PF00124

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z6NDH3 1-58 MSALGCPQDMFSDTAIQLQPVFAQWIQNTHTLAPCTTAPGATESTSLTWGGGDLVAVA
A0A287J4K2 1-65 MSALGRPQDMFLDTAIQLQPIFAQWVQNIHATAPGVTTPGATTSTSLTWGGGELVALGGKVALLP
A0A835HD36 152-225 None
A0A2G3ASJ4 104-177 None
A0A3B6PKD4 372-467 None
A0A1R3KZH4 50-123 None
A0A2G3CMI3 165-224 None
A0A5N6P8X7 1-60 None
A0A5D2KKH8 327-400 None
A0A7J9LF24 1-54 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.