DPCstruct | MC56023

Metacluster Properties and Pfam Annotations

Number of structural domains126
Mean domain length (aa)167 ± 36 aa
Standard deviation of domain lengths36.11
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.88
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)32.22
Pfam Score95.83
Assigned Pfam label(s) CL0231- PF21186- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C5L5K5 2-163 PHRSFTELVGLIEKLRGEDGCPWDGAQTHATLRPYVLEEAYETIAAIDTGDPAAIADELGDLLLQVLLHAQIASKAGEFTIDDVIEN…
A5IK56 2-115 VERLLEIIERSLEKCPWLEKQSIETLLEALASEIEEVTEAVKKNDLANLEEEVGDLIYDALLVAAVAQRDYGIDLERAIQKVVEKIS…
A0A379ACN2 3-144 None
A0A2N6VRA5 21-237 None
A0A4Z0IXD0 2-129 None
E7GTZ4 64-200 None
A0A2N6FGR7 36-211 None
A0A437UX62 168-368 None
A0A2S5IZ25 1-211 None
A0A7C5JR65 2-204 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.