DPCstruct | MC56013

Metacluster Properties and Pfam Annotations

Number of structural domains135
Mean domain length (aa)274 ± 43 aa
Standard deviation of domain lengths42.68
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score87.34
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)20.21
Pfam Score97.20
Assigned Pfam label(s) CL0044- PF03477- PF11307- PF15686

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A654ZTL8 1-251 MSDDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFEEAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIF…
A0A315EKB6 454-724 FDWSYEAQASSVQNLYAKSKHAQWDAAERINWQQDLDPENPFGYDDRLMPLSGTEAWAKASSKERANVRHQYQAYMVNQFLHGEQAA…
A0A4W6EJ60 5-194 None
A0A370H9I4 41-279 None
A0A2K6SUK7 2-312 None
A0A2S8BHP3 8-275 None
A0A3S6Z1Q8 4-245 None
P36603 73-366 None
A0A183SC55 1-258 None
A0A7C8CIJ6 37-304 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.