DPCstruct | MC56010

Metacluster Properties and Pfam Annotations

Number of structural domains65
Mean domain length (aa)220 ± 41 aa
Standard deviation of domain lengths40.58
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score77.96
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)29.74
Pfam Score97.92
Assigned Pfam label(s) CL0016- PF04176- PF11277

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5A8CMB1 26-237 ETIGGWSFRSVSAPIASSARIEEVEAALSLPHGVPVPEACFADNSLTIRHDASGTELRINAVDALRSWHSRQSRIAADAGGVVCATS…
A0A5F4CGU3 17-228 PWKLTAAKTHIMKSADVEKLADELHMPSLPEMMFGDNVLRIQHGSGFGIEFNATDALRCVNNYQGMLKVACAEEWQESRTEGEHSKE…
A0A0N1IIN3 5-299 None
A0A0D0T5F0 7-194 None
A0A093XQN1 15-241 None
A0A2G5UK67 358-522 None
A0A2U1QMD9 2-223 None
A0A7J0ET87 10-140 None
A0A5F7ZSY3 2-143 None
A0A7S1KLA3 6-297 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.