DPCstruct | MC55978

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)103 ± 7 aa
Standard deviation of domain lengths6.98
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score74.42
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)53.10
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A068VQF8 151-260 KNIADLFPSKEAQEEVRKYEEIKNQAAANLKSVYDEIRPTIEKHERDSQDDVPPSVGTKWVGAHCAKYKADLNFSASVIKNFLNIAQ…
A0A7C9ANF0 1-109 KDAVKLLASKEAEQEILTFEEIRKDASSNLEALYDEIRPAIEEHERDTQDSVPTSVAEKWIEASCLKMKTEFDLYFSVVKNLMFSPK…
A0A4S8IZF9 430-521 None
A0A061FHJ3 241-349 None
A0A438JWE9 1-92 None
A0A835R7G9 259-362 None
Q8L819 407-512 None
A0A2P5BV25 288-396 None
A0A1U7VVK1 88-178 None
A0A5N6RM22 395-501 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.