DPCstruct | MC55972

Metacluster Properties and Pfam Annotations

Number of structural domains726
Mean domain length (aa)146 ± 26 aa
Standard deviation of domain lengths25.73
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score77.26
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)33.64
Pfam Score98.79
Assigned Pfam label(s) CL0023- PF05911- PF16183- PF16540

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A818IL84 210-364 None
A0A1Y1YU38 469-593 None
Q8I235 1129-1307 None
A0A812R1B8 47-203 None
A0A812QK28 270-393 None
A0A1X0Q6D3 94-205 None
A0A4Y2QZ71 405-578 None
A0A835HSR7 6-117 None
A0A226D732 186-364 None
A0A4D9DZ96 589-756 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.