DPCstruct | MC55972

Metacluster Properties and Pfam Annotations

Number of structural domains726
Mean domain length (aa)146 ± 26 aa
Standard deviation of domain lengths25.73
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score77.26
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)33.64
Pfam Score98.79
Assigned Pfam label(s) CL0023- PF05911- PF16183- PF16540

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A672MTH6 316-469 None
A0A7J7PLV9 187-347 None
A0A7J7PSN7 622-781 None
A0A7S1F1D9 226-386 None
A0A1B0D8E2 215-333 None
A0A1B0DQ23 86-238 None
A0A4D6KMC6 205-389 None
A0A5E8BYG1 219-366 None
A0A388M746 107-270 None
U6GCM1 12-191 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.