DPCstruct | MC55972

Metacluster Properties and Pfam Annotations

Number of structural domains726
Mean domain length (aa)146 ± 26 aa
Standard deviation of domain lengths25.73
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score77.26
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)33.64
Pfam Score98.79
Assigned Pfam label(s) CL0023- PF05911- PF16183- PF16540

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S4DPC2 984-1104 None
A0A6P5W2X9 28-171 None
A0A2V2VM39 1-160 None
A0A3Q0ILH5 15-127 None
A0A4Y7JD03 2-78 None
A0A821FJF9 112-250 None
A0A7R9UEK4 90-248 None
A0A177WBU0 228-372 None
A0A812J0N9 190-344 None
A0A7N0TKB4 106-271 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.