DPCstruct | MC55972

Metacluster Properties and Pfam Annotations

Number of structural domains726
Mean domain length (aa)146 ± 26 aa
Standard deviation of domain lengths25.73
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score77.26
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)33.64
Pfam Score98.79
Assigned Pfam label(s) CL0023- PF05911- PF16183- PF16540

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183KW58 47-183 None
A4I995 328-522 None
A0A7R9DE76 226-404 None
A0A834MC66 197-346 None
D2VDS8 278-455 None
A0A7S2GX86 6-137 None
A0A7R9FNN8 340-530 None
A0A3P8SSK4 418-605 None
V6LKF1 158-303 None
A0A6G0YN77 299-448 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.