DPCstruct | MC55972

Metacluster Properties and Pfam Annotations

Number of structural domains726
Mean domain length (aa)146 ± 26 aa
Standard deviation of domain lengths25.73
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score77.26
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)33.64
Pfam Score98.79
Assigned Pfam label(s) CL0023- PF05911- PF16183- PF16540

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y1WI54 32-209 None
A0A2T7PSI2 46-203 None
A0A1S3LSZ0 119-244 None
A0A662Y1N3 541-702 None
A0A817FBQ1 197-336 None
A0A7S3KV68 127-271 None
A0A1S3YA44 607-763 None
A0A183W8B6 1-167 None
A0A4D9AC85 550-711 None
A0A0D2RIR3 2-129 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.