DPCstruct | MC55961

Metacluster Properties and Pfam Annotations

Number of structural domains54
Mean domain length (aa)291 ± 58 aa
Standard deviation of domain lengths58.03
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.84
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)27.88
Pfam Score72.72
Assigned Pfam label(s) CL0123- CL0125- CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H9G8J9 2-224 LVSLAGPNPQVAKKTHILVPLGSPLSDLSWSAELRDTGTNTMTIRVNTSPEAVIGKYQFSVKTRSKAGEYQAPFDPRYEIYILFNPW…
A0A2I0TI72 9-318 YSVESQGADLTPTHISWQPSLNASAHHTDKYANTELTVRRGQGFTISLYFNRPRQNGESLAFVTEIGPSPSESHRTKAVFKLSEAGA…
A0A1I8F7F4 309-651 None
A0A6A4JYQ3 311-613 None
A0A0C2MKW2 575-781 None
A0A7R9Q356 62-292 None
A0A4Z2GKC5 31-345 None
A0A183H7Q4 306-573 None
A0A6P8GKT3 262-617 None
A0A7M6DR73 145-462 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.