DPCstruct | MC55946

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)112 ± 11 aa
Standard deviation of domain lengths11.11
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score89.53
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)39.26
Pfam Score86.11
Assigned Pfam label(s) CL0597- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0T084 1-139 MLAAANAGADVVDVAVDAMSGMTSQPSMGALVACARGTPLDTGIALERVFEYSEYWEGARGLYAAFDCTATMKSGNADVYENEIPGG…
A0A0K2R0P0 73-180 LLAAVDAGVDAVDVASASLAGTTSQPSASALVAALAHTQRDTGLSLDAVSSLEPYWEAVRRVYAPFESGLPGPTGRVYQHEIPGGQL…
A0A832U5Z9 54-167 None
A0A8B1NAS3 215-331 None
A0A3Q9LGD1 64-180 None
A0A7E4RXI9 112-226 None
A0A512UKP3 3-101 None
H7EK57 143-251 None
A0A4R1Q070 36-149 None
A0A379V0J0 1-124 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.