DPCstruct | MC55888

Metacluster Properties and Pfam Annotations

Number of structural domains378
Mean domain length (aa)114 ± 19 aa
Standard deviation of domain lengths19.38
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.80
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)22.37
Pfam Score98.16
Assigned Pfam label(s) CL0113- PF01556- CL0123- PF00684- PF01025

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183LU08 12-131 None
A0A7J0EFX0 175-292 None
A0A2P5DIT8 45-159 None
A0A7J0ED41 9-120 None
A0A2H1YK02 114-206 None
A0A7V6J1Q2 177-318 None
A0A5J4W7Y5 497-622 None
A0A0A2W5C1 159-283 None
A0A5A7S6B7 76-187 None
A0A7V1RE82 69-187 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.