DPCstruct | MC55888

Metacluster Properties and Pfam Annotations

Number of structural domains378
Mean domain length (aa)114 ± 19 aa
Standard deviation of domain lengths19.38
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.80
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)22.37
Pfam Score98.16
Assigned Pfam label(s) CL0113- PF01556- CL0123- PF00684- PF01025

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4T0R322 217-341 RIRLQGEGDEVPGAKPASLVFRLRTKKHDTFRVSGYDLAINIKLTLLEALSGFEKIICHHLDGRTVKVSVPQGRVIQPNETLCLRDQ…
A3IPY9 1-80 MPVTPSEAILGGSVEVPTIDGLVKMTVPKGVRPGQRLRLANKGYPDASGKRGDQLVEIQIAIPSEVSDEEIALYQQIREK
A0A1Q6Z1I9 67-146 None
A0A654HC41 37-163 None
A0A6U5GHA0 40-169 None
A0A1B0C5J2 2-76 None
A0A2G8LNX5 13-126 None
A0A6D2I0V1 628-745 None
B0EIW1 32-171 None
A0A1B0C165 221-344 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.