DPCstruct | MC55878

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)199 ± 37 aa
Standard deviation of domain lengths36.76
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score76.11
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)27.09
Pfam Score100.00
Assigned Pfam label(s) CL0128

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H0VG75 3-183 EQSLISSEKWLQRHGLKANKLSLRQILSQIGFPHCEDYVTSLGRPVASRYADGLFPRFCRAEDGRVYNLTANSELIHQLVEHLAQAV…
A0A6P7U0K7 50-254 MLKSSNGKNITTNQTDKSKFDEFYQMNMIQITQDLLNSEKSNNVPPEAREQISADKWIHKYGLVNNKLSWDFILKKIGFKKSEEYVY…
A0A835NWE4 44-236 None
A0A835NYQ7 4-201 None
G1SW02 84-258 None
B7Z7Q7 213-427 None
A0A822DDI4 1-198 None
A0A6P8H7T7 81-283 None
A0A819Z5C2 19-224 None
A0A183MWA7 445-624 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.