DPCstruct | MC55833

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)162 ± 25 aa
Standard deviation of domain lengths25.48
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score93.17
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)30.85
Pfam Score100.00
Assigned Pfam label(s) PF05681

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A378C7M3 41-201 KVDPQALTLLAQHAFHDASFMLRPAHQQQVADILNDPEASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIMGKKGQRVWTGGGD…
H1D995 8-161 MVTNEVEKMCMAANYYVDPEVLKKINRAYRETEKSPLAKNVLQQILENDAIAEEERVPMCQDTGMAVIFLEIGTEVYIPGDIYEAIQ…
A0A654HEF7 293-475 None
A0A1J1H7C8 117-324 None
A0A6P5WBQ1 189-392 None
A0A2G6LX78 2-126 None
A0A4R9LS92 6-173 None
A0A350M0A9 3-168 None
A0A388NRQ0 32-212 None
A0A7H1NR15 650-873 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.