DPCstruct | MC55725

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)216 ± 31 aa
Standard deviation of domain lengths30.52
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score65.68
Mean fraction of residues predicted as intrinsically disordered0.45
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)29.96
Pfam Score100.00
Assigned Pfam label(s) CL0188

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A164I8Y6 1-197 MIFFYGFLSHRPQGEDVPNFPELRELGDLSDGMSLLGLLAFYAPDLVDWTRIATNEPFSMADCLYNLELVHKFCSESIPNNIFHLGL…
A1ZAU8 148-380 NNYQAPTGQSYEQALLGWISHACAALKKRIIKEVDAGLPDDNGSRLQTPDIPPVRDFQDLCDGICLALLISYYCPKVVPWTSVRINY…
A0A2A2K839 159-418 None
A0A674C1N5 174-436 None
A0A1I7WPW1 141-310 None
A0A182TR31 1-261 None
A0A4W5RKD3 240-420 None
H2PA85 168-368 None
A0A3S2PIG2 220-428 None
A0A1B8XU82 1-200 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.