DPCstruct | MC55619

Metacluster Properties and Pfam Annotations

Number of structural domains31
Mean domain length (aa)93 ± 10 aa
Standard deviation of domain lengths10.33
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score81.25
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)35.40
Pfam Score97.92
Assigned Pfam label(s) CL0236- PF01253

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A182KGG4 2-82 AIHFHEILKTFYTLGCEDEALCYGACRVYIYLKEEKHMHDVQYMYEKQLQLFYLTARKEPDALTDLFVPALTTDAFNLVQL
A0A672T3D3 2-98 DEVNRADPPSWIQQHAYQDLMHLDVGDSAQVYAAFLVYMDLTEVRKWKEVVGVSCPELQAVLLEGREKEGETVQMVYPLPSHRSIKH…
A0A6I9KGR3 17-89 None
A0A4W6FJF3 10-103 None
H3AXP3 7-113 None
A0A4W2H0H6 250-361 None
A0A2D4PS01 35-128 None
A7RUN4 453-543 None
A0A2K6B7H4 27-116 None
A0A7J8BHJ7 5-89 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.