DPCstruct | MC55486

Metacluster Properties and Pfam Annotations

Number of structural domains317
Mean domain length (aa)218 ± 47 aa
Standard deviation of domain lengths46.54
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score86.13
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)13.17
Pfam Score44.19
Assigned Pfam label(s) PF12294- PF11185- CL0184- CL0113- PF06128

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y5TJJ6 4-231 RFIFRQVYFGDLPTFLADGEIRAKNHGSPQLCHQTSYQEIVNRRGTNEFPMPCGGVVNDYVPFYFSPLTSFTYAIHSGNVPLISPSG…
A0A8A3TVN6 28-235 SFTYEELNFIFDIFKKGRIRKIENIKFLYYIVPIENLENIIKSGKIECRNNVLKKGKRINDPSDKNVQKRRAEKYIYRKYNIHNFVG…
A0A0N0ARP3 3-201 None
A0A812LMA8 180-400 None
A0A359LUB1 6-172 None
A0A1X9SM09 7-192 None
A0A7W8XIZ1 68-307 None
A0A349MFN0 27-249 None
U1GZ84 13-209 None
A0A1C5MM23 292-501 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.