DPCstruct | MC5546

Metacluster Properties and Pfam Annotations

Number of structural domains5
Mean domain length (aa)144 ± 20 aa
Standard deviation of domain lengths19.91
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score80.57
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)30.26
Pfam Score100.00
Assigned Pfam label(s) CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S9HXE4 19-148 WAKEDAQGNCPQAGPETEQFSLGSCIFNIRYGHPPYAELESPVWYEYMSHQRYPPTPKGDDIGDIIQACWRGDYASIEQLEDHISLV…
A0A428R7J3 439-565 WARVLGSEAGAQRGTFGINGLQTEQFAIGSLLFTMSRGYEPYAELEPGPHIVDLLQDMKFPDLGHGYLDTIIDACWKGLYGSVESLA…
F2S3I6 175-356 None
A0A2S4L4I6 1-142 None
A0A507B5U3 1091-1227 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.