DPCstruct | MC55452

Metacluster Properties and Pfam Annotations

Number of structural domains474
Mean domain length (aa)158 ± 24 aa
Standard deviation of domain lengths24.32
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score78.08
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.21
Pfam Score69.97
Assigned Pfam label(s) CL0125- PF20174- PF16044- PF12597- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
X0LF70 9-177 RETQRAVFLVTTPISFGVLEVSQSSYKLLARHVGMSLNSVSHWAVCVIDRGLGKCYCYDLMSDRLELTMLGKNYFRVAVITEEFVET…
M3BB79 2-100 EIELYVYDLTRGMARAMSRQFLGVQIDAVYHTALVFGGIEYFFGAGVQTCYPGTTHHGQPMEVIKLGTTQLPLEIILEYLESLKEVY…
A0A7S4PJL5 102-257 None
A0A7S4RMQ5 19-184 None
G3J5Y4 11-171 None
A0A7S4R0N5 205-367 None
A0A2B4S185 105-282 None
E9FR33 18-225 None
A0A199VYN1 2-97 None
A0A061QP73 2-110 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.