DPCstruct | MC55392

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)128 ± 9 aa
Standard deviation of domain lengths8.59
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score76.24
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)43.91
Pfam Score100.00
Assigned Pfam label(s) PF10155

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3CLL4 1-126 MRCDRFCEDELAWLNPTEPDHSVMWDRSMCVKNSTGVEIKRIMSKAFKSPLLAQQQSQLLAELEKDPRLVYHIGLTPAKLPDLVENN…
A0A7S3LRX9 1-120 MKTGANDVVWLNPSDAPGLMWDVTMCEDSSRGAEVRELMTKAFKGPLVAVQQKHVLQELEADPKLVYHCGLTPQRLPDLVENNPVIA…
A0A1S8VDE4 116-246 None
X6P788 1-111 None
A0A182IY47 223-343 None
A0A7I4CLW1 128-265 None
T1KZP7 28-163 None
A0A164X4F3 109-245 None
A0A182FHF5 687-827 None
A0A5J5CDD0 189-328 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.