DPCstruct | MC55180

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)153 ± 16 aa
Standard deviation of domain lengths16.30
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score80.53
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)29.77
Pfam Score100.00
Assigned Pfam label(s) PF12520

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A395HF86 3-156 HMFVAPPEEECLIQTSESSFRTARVSPMEQFELRYRQVWLYAMRHYPLMPPDPKTDAKLFANFNRAKADEHTVCEMARLAYRLGFRS…
A0A6A6I425 33-231 LGIFFEMLKYLEPICDTLKQLIRTKMKGTIRRSLFGSFFPPEKVTVQKSESHAMELRGQLDKAAEIAYIQLWAFCARHFNGLTTFTP…
A0A4Z1L298 378-510 None
A0A7R7VE23 137-278 None
A0A084BCK0 361-512 None
A0A5N6X1H1 466-606 None
A0A1V8S7G2 124-258 None
A0A2H3FKE2 370-493 None
A0A4V3SIE6 7-187 None
A0A0C3GBH3 1-145 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.