DPCstruct | MC55176

Metacluster Properties and Pfam Annotations

Number of structural domains211
Mean domain length (aa)186 ± 36 aa
Standard deviation of domain lengths36.09
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.21
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)12.84
Pfam Score26.42
Assigned Pfam label(s) PF15384- PF09302- PF06632- CL0097- PF16531

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P4ZKD3 19-206 RSWQKFELEGQNFLLKTHVDHREGYEFLFTDLTCLWHEKMDKEEVKKRCKTLNPRFEAPLPTILRLLQDNTETKKDSTDYTIQHQGE…
A0A3Q2CGU8 16-186 PWLPVTIDGVQLLSKPWFGETAYRILLTDMQSVWEEKIEAAAVEKRSQELNRRLRASAAAFFSHLCEVAQPCLSGGQQTGGEVQMSV…
A0A668W0P8 1-157 None
A0A812YAP6 506-687 None
A0A1Y1V4W9 162-451 None
A0A1A9ZXB9 1-221 None
A0A1S3MSA8 15-243 None
A0A1J8PN33 34-197 None
A0A5E4PVY5 3-125 None
A0A815TMT7 3-186 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.