DPCstruct | MC55086

Metacluster Properties and Pfam Annotations

Number of structural domains8903
Mean domain length (aa)189 ± 33 aa
Standard deviation of domain lengths32.53
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.75
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.34
Mean intra-cluster sequence similarity (%)10.79
Pfam Score90.63
Assigned Pfam label(s) PF12294- PF15756- CL0113- CL0110- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y2DID4 470-642 None
A0A4Y2DEJ6 168-334 None
A0A4Y2DCX8 2-178 None
A0A178DIV3 12-220 None
A0A251X6Y6 1-222 None
A0A7G5YYG4 2-133 None
A0A2J8UC17 245-447 None
A0A1X4J1T1 18-205 None
A0A1X4IUH7 602-751 None
A0A1G2ER74 741-919 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.