DPCstruct | MC55086

Metacluster Properties and Pfam Annotations

Number of structural domains8903
Mean domain length (aa)189 ± 33 aa
Standard deviation of domain lengths32.53
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.75
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.34
Mean intra-cluster sequence similarity (%)10.79
Pfam Score90.63
Assigned Pfam label(s) PF12294- PF15756- CL0113- CL0110- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C6QEQ7 31-196 VTWDKWTANNGGWKIEGYVNADGKSNPITAYAAVDQNGPLVTVEWTVQFIEHTFSLGPAAGVHIMADASDPTKANSYLIFQDNGFIR…
A0A0D1IL93 6-164 TSPSYNKFDCGENRSVQTYGYGLYEVRMKPAKNTGIVSSFFTYTGPTDGTPWDEIDIEFLGKDTTKVQFNYYTNGAGNHEKIVDLGF…
A0A7Y0N925 9-167 None
A0A497NZN0 22-223 None
A0A2D5WIY2 13-180 None
A0A2D9MZG7 8-185 None
A0A2D9MZY6 5-153 None
W8KSK1 257-457 None
A0A7W0Q3P7 26-222 None
A0A194VBU8 29-290 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.