DPCstruct | MC55032

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)177 ± 27 aa
Standard deviation of domain lengths27.20
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score86.28
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)31.74
Pfam Score91.82
Assigned Pfam label(s) PF05591- PF05943

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X1YIE1 27-191 KTLAQQALENTVTLTSDAYSTIQEIIAEIDRKLSEQINKILHHQEFQALEGAWRGLHYLVNNTETDELLKIRFMDISKKELGRTLKR…
A0A827MJL8 1-131 HHPEFQKVESLWRGVKSLVDKTDFRRNVKIELLDLSKDDLRQDFEDAPEIIQSGLYLQTYVAEYDTPGGEPIAALISAWEFDASAQD…
A0A336QZL9 1-173 None
A0A285Z8U3 22-220 None
A0A6J5BUK2 51-239 None
A0A447WC42 5-232 None
A0A376VPT9 2-148 None
A0A2H0IB52 3-140 None
A0A5E7MF80 46-237 None
A0A7V3JJY5 48-213 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.