DPCstruct | MC55023

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)201 ± 27 aa
Standard deviation of domain lengths26.95
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score80.38
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)43.47
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A421FRB7 2-196 PVMLMTIFGVTGYLSDGTFLIEYKDSYFAYSQMDLVMSGGCTPCHVICKRVLHQMATFNHEALMSKPTFEDLYTATSWDYSILSAEA…
A0A6A4CHD0 33-210 AFTEQDMTMSGGCSGCIGPCKITLLKYTLFNGSAFVSSPVFNAFVALGPVESLYDFTSLSPEALALGESLDRNGAVCQSGINEWGAT…
A0A6A3KBU9 118-311 None
W2XZ52 15-184 None
A0A6A3V6Z8 43-238 None
G4ZUX9 1-239 None
A0A6A4EWZ0 1-163 None
H3GIG6 13-208 None
H3GIA8 14-245 None
A0A6A3PU76 53-251 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.