DPCstruct | MC55019

Metacluster Properties and Pfam Annotations

Number of structural domains361
Mean domain length (aa)132 ± 25 aa
Standard deviation of domain lengths24.61
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score73.62
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)30.79
Pfam Score99.34
Assigned Pfam label(s) CL0123- CL0192- CL0167- PF08430

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0F8ULB4 387-517 EPHKAYGEALEYTGSYSLYDANADPPYSQLIYEALRTAPGKKLPLQGIYGWFEKNTAKGKDGNSKGWQNSIRHNLSMNAGFEAIREE…
S4PY66 13-113 EPKPQHSYIGLIAMAILNSPDCKLVLSDIYQHILDNYPYFRSRGPGWRNSIRHNLSLNDCFVKAGRSANGKGHYWAIHPANIEDFRK…
A0A654HXK8 210-319 None
W5LXW9 25-178 None
A0A1V8SWU0 123-273 None
A0A1D2NB64 488-613 None
A0A7E4W3R1 149-274 None
H3AP50 30-146 None
R4WDS6 10-161 None
A0A1Y1NLT0 459-604 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.