DPCstruct | MC54997

Metacluster Properties and Pfam Annotations

Number of structural domains437
Mean domain length (aa)164 ± 38 aa
Standard deviation of domain lengths37.56
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score87.65
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)19.87
Pfam Score99.53
Assigned Pfam label(s) CL0039- PF12100- CL0214

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D5ZHP8 2-105 SRQYVTTAIDYPNAAPHMGHVLEKVLADVTARWFRLRGDAVRFQIGTDEHGTKIQRTAESEGVTSKELVDRNVPLFEDLYKRLNISH…
T2JVM4 6-149 TKPKKFALTTPLYYVNGVPHIGSAYTTIIADVIARHKRLIGDEVLLITGTDEHGQKIQRTAEEKGLAPQKHCDEIVSSFEELWQKLE…
A0A2D6QME9 16-193 None
A0A1Y1NK07 33-146 None
A0A084RTR0 23-146 None
A0A7R9LFB9 37-180 None
A0A1B0C1R2 1-175 None
A0A1B0C165 447-678 None
A0A1Q9C2M9 78-230 None
A0A6A6KX30 2-259 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.