DPCstruct | MC54993

Metacluster Properties and Pfam Annotations

Number of structural domains75
Mean domain length (aa)109 ± 8 aa
Standard deviation of domain lengths8.19
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score80.52
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)39.68
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T2JMJ6 1-109 MDNTQFRGAFSRETNTIYFSEKLVRDTVLQFETVEDINSDNQYIQAFVAVWLEEIGHSVEAQLNEEEIAGDEGRILAAVVIGESYTR…
A0A552Q277 58-164 PEIEVVNSSVLGSANGAYGISTNKIYLSESFFASASLDALVAVILEEIGHYVDAQVNRVDTVGDEGELFSHLVRGVNLTEAELTYIQ…
A0A0D6AV49 57-162 None
A0A6I5PA21 95-195 None
A0A846DA14 52-160 None
I4G4M8 57-167 None
A0A350Y115 60-197 None
Q118G9 85-210 None
A0A2Z2NRU5 125-239 None
I4FVR6 57-162 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.