DPCstruct | MC54948

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)129 ± 19 aa
Standard deviation of domain lengths18.87
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score88.25
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)20.26
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A858WZE7 9-142 REVIGCYLKELDERLAPATEREVGASFTALLLAFPAQPLSEAAARIRAGAYFEALDGEPAWAIARAGSRWLRGEVEGNLAFAPSPPQ…
A0A5B9CX42 11-119 EVQTLQDCNRLQTLLSRQVTVEHIGAAAYLLSGLKIPANTDSDVIALNYSIALADASEHALKRAVKDVIRGEAKGLSKTFMPTGAEL…
A0A1P8QX70 2-129 None
A0A285TXR2 61-169 None
A0A2P7BPT5 35-138 None
E6YYZ7 342-489 None
A0A512IS74 15-159 None
A0A7Z8R830 6-161 None
A0A4Q8ZYH2 3-149 None
A0A336NDH3 1-110 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.