DPCstruct | MC54937

Metacluster Properties and Pfam Annotations

Number of structural domains117
Mean domain length (aa)190 ± 32 aa
Standard deviation of domain lengths32.25
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score79.32
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)14.52
Pfam Score62.60
Assigned Pfam label(s) PF21222- PF20520- CL0721

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L5JN20 2-163 GIELTVQYMVSVFSRQSYFNIDPNATQASGNCGSQVSNLLLNFQGGFVNLTFTKDENSYYISEVGAYLTVSNPEKIYQGMKSAVMFE…
C0PUW8 2-188 LQMAAQLNFTYEAREGNFTTGLYNIPSNASVEDAECKSQTTQFIHLIWGPETSKQSLIMYFNKSNDTTVLSFMQIHLALLPEDFPDA…
A0A6P6CE05 113-292 None
A0A3B5PS29 48-247 None
F7E397 88-277 None
A0A3Q0J901 1-164 None
A0A1B0BV32 2-144 None
A0A7E4VIK9 25-280 None
A0A0C2I9U5 12-250 None
A0A0C2IXC7 6-181 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.