DPCstruct | MC54758

Metacluster Properties and Pfam Annotations

Number of structural domains53
Mean domain length (aa)78 ± 16 aa
Standard deviation of domain lengths16.09
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score82.38
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)57.67
Pfam Score82.57
Assigned Pfam label(s) CL0123- PF05180- PF08069- CL0600

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U1EPA9 29-95 GRMHAPGKGLSQLALPYHCSTPIWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQSLIHRL
A0A822ZCE0 1-88 MHSRGKGISTSALPYKRTPPFWLKISSQDVEENICKFAKKGLTPSQIGVILHDFHGIAQVKSVTGNKILRILKAHGLAPEIPEDLYHL
A0A4Y1QZW5 2-79 None
A0A166C8R9 1-92 None
A0A212CF44 1-50 None
A0A146HBY4 83-173 None
A0A7R9ACI1 435-523 None
A0A5A7VKU6 66-160 None
A0A816JLZ1 26-116 None
A0A5N5KQC3 1-64 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.