DPCstruct | MC54650

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)175 ± 28 aa
Standard deviation of domain lengths28.14
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.04
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)30.24
Pfam Score100.00
Assigned Pfam label(s) CL0175

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E2LCL3 6-207 RTIRLPTDKEVDPEIQPFVKSGMDFCMETLLNLTPDERNRTREMLKRNKVTYFRQALDAMGREDDVDEAFWYALDKVDFFPRPWEKQ…
A0A4V4HIG7 8-150 GTWMQNMLQQWGWDDFKLDPAVVFAMDNVDFHPRPWEGLLSKVEGNKRMQEWNAAVDEYIKTPGDTRNRIDIEIEAKIGPHGGPLYR…
A0A2H3BWJ3 120-344 None
A0A4Y7QAC6 219-369 None
A0A4Y7QAG9 24-200 None
A0A401H0G0 31-236 None
B8PAA6 298-481 None
M2P7Q1 58-244 None
A0A4S4M5J9 23-162 None
A0A4Y9YSQ8 338-536 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.