DPCstruct | MC54616

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)169 ± 14 aa
Standard deviation of domain lengths13.94
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score81.88
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)27.17
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E2BP73 318-482 DLDCFVFECNDTMLGLAILSRYHVEDYVSMQSIHQDDYGRLLHFVLTPIFFAYHRFFFREIARLSGLTVIFYRLQHEDESALTRKRP…
A0A7S3QR29 123-274 AVVASVQGEVVGLATVSTSVDLVMLKANFSLSHLVNLPDQMSSEHAEIDMVCLNPIFAHRARELLSGVHRILKKTVLYYALPPGQAI…
A0A2I0TA09 97-264 None
A0A1Y1KGI0 303-474 None
A0A3Q0CU67 1-158 None
A0EGL6 282-461 None
Q23F13 852-1036 None
A0A7S3QR82 123-272 None
A0A0W8DMU5 357-549 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.