DPCstruct | MC54572

Metacluster Properties and Pfam Annotations

Number of structural domains227
Mean domain length (aa)285 ± 75 aa
Standard deviation of domain lengths74.76
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score87.08
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)18.43
Pfam Score77.39
Assigned Pfam label(s) PF16350- CL0289- PF08170- CL0061- CL0740

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D8RHI4 5-329 None
A0A7J6S1I7 11-255 None
A0A354FLD1 16-393 None
A0A7S1T0Q4 1-150 None
A0A5K4EVT3 17-253 None
A0A7R8H5U0 14-221 None
A0A7J2S3B5 3-220 None
A0A6L5CLD7 281-569 None
A0A2V8I8E1 21-376 None
A0A151TJJ4 25-282 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.