DPCstruct | MC54572

Metacluster Properties and Pfam Annotations

Number of structural domains227
Mean domain length (aa)285 ± 75 aa
Standard deviation of domain lengths74.76
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score87.08
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)18.43
Pfam Score77.39
Assigned Pfam label(s) PF16350- CL0289- PF08170- CL0061- CL0740

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A4BKV9 23-250 None
A0A0M9A9S2 206-580 None
A0A7C5APS2 832-1220 None
A0A5P1EEP7 703-1038 None
A0A7C4UVP9 304-682 None
A0A846F7Z2 3-177 None
A0A250WU06 64-411 None
A0A800E525 12-176 None
A0A7Y5BWM1 262-646 None
A0A7W0TK82 9-337 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.