DPCstruct | MC54572

Metacluster Properties and Pfam Annotations

Number of structural domains227
Mean domain length (aa)285 ± 75 aa
Standard deviation of domain lengths74.76
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score87.08
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)18.43
Pfam Score77.39
Assigned Pfam label(s) PF16350- CL0289- PF08170- CL0061- CL0740

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A538LHD8 22-352 EGWQWPNHFGDPVAEHEAVRNDVGVWDESPLRKWDFRGPDALRAADRIFTNDMLGLATGQIRYAPFCDADGKMVGDGTVFKFDDGHA…
A0A1F2VCM5 13-286 QGNYNFVLDTHGHILADARIFRLDAESYLIDSEPQRIEIIRQALDHHIISDVVELEDWSARLACLALEGPCAREVLRETIGFDPPHM…
A0A437UXM7 151-391 None
A0A812MUI1 135-466 None
A0A7X7R7Q1 11-170 None
A0A0D8XC31 1-177 None
A0A7S2SSE3 4-338 None
A0A194V5U4 483-832 None
A0A7X0U4D0 521-858 None
A0A7J0FX28 36-356 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.