DPCstruct | MC54449

Metacluster Properties and Pfam Annotations

Number of structural domains74
Mean domain length (aa)262 ± 38 aa
Standard deviation of domain lengths38.13
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score79.63
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)24.47
Pfam Score74.26
Assigned Pfam label(s) CL0161- PF05524- CL0198- CL0364- PF00381

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U9HTW0 2-193 HEQQRLRQALQQTLGDLNRLAERTATLIGKPQAGIFGAHSMLLDDPDLQQAAYTRIAQQCCSAEQAWRQELEAVAADYRALDDDYLR…
A0A0W7TQ69 265-536 PNKRQKQIFKAREPLEQEEDGGGAACGLCRETGRCADLKYITAVPASAGLAVGTVRYLRHTQSGLGRAVRSPKEEQEAFENAVREAQ…
A0A381ETG7 118-350 None
A0A1C6HI28 5-261 None
A0A426TYW5 16-277 None
A0A0W1A545 158-430 None
A0A2N5E221 52-389 None
A0A4U1LZH9 346-630 None
A0A7X0TV99 2-213 None
A0A4U9D6J9 32-313 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.