DPCstruct | MC54442

Metacluster Properties and Pfam Annotations

Number of structural domains873
Mean domain length (aa)142 ± 27 aa
Standard deviation of domain lengths27.30
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.75
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)22.70
Pfam Score98.05
Assigned Pfam label(s) CL0023- CL0229- PF12024- PF06001- PF00439

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3P7Z5I5 7-110 QEAKQLAEKIRPILNALRSHILAGPFQKPVTVDEAPDYYDIIVFPIDLSTMWERLKSNYYVTKSLFIADMMRMFHNCRTYNQQDSYL…
U4UA64 20-176 ASGSGIPSAVGQPGVLGQKSKEKLNDHLKACSEILKELFSKKHCTYAWPFYKPVDAEMLGLHDYHDIIKHPMDLGTIKEKLDNREYH…
A0A0K0EH23 392-658 None
A0A0K0DWW8 1177-1351 None
A0A0V0QQZ7 13-149 None
A0A0V0QIE6 5-158 None
A0A182THV9 41-192 None
A0A101MBJ4 4-184 None
A0A7S1VD53 2-129 None
A0A7M5WJD5 852-985 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.