DPCstruct | MC54437

Metacluster Properties and Pfam Annotations

Number of structural domains319
Mean domain length (aa)250 ± 49 aa
Standard deviation of domain lengths49.07
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.23
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)19.14
Pfam Score98.58
Assigned Pfam label(s) CL0023- CL0743- CL0220- PF03826- PF04435

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P5W5C7 5-206 LQAALPDCKITNLTTDWNSGVNLAALLDYCQPGLFPHWRSLDPSQSVRNCTNAMNLAQREFGVPKVLEPEYLASPWLDELSGMTYLS…
A0A1I7YZM1 12-281 FRMSSKYQHDKIQKKTFTKWINYHLETHNSSRQVEDLFEDLRDGVLLCHLIEVLTGEALPVHKGRVSKRVHHISNLTTALTVLRRRG…
A0A1U8P546 8-252 None
A0A2I4D4S6 45-239 None
A0A0K0E918 382-628 None
A0A821LKI1 115-322 None
A0A6P8IAZ9 724-907 None
A0A1B0BMH3 164-485 None
A0A654HZW7 623-916 None
A0A034V9W6 41-206 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.