DPCstruct | MC54344

Metacluster Properties and Pfam Annotations

Number of structural domains785
Mean domain length (aa)192 ± 50 aa
Standard deviation of domain lengths49.78
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score80.20
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)16.00
Pfam Score85.40
Assigned Pfam label(s) CL0063- CL0479- CL0123- PF13224- CL0248

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I6APC2 10-171 None
I6B2W6 198-407 None
A0A846JVH9 16-205 None
A0A2D6XKC7 28-192 None
J8VQ28 1-209 None
A0A840CS83 261-431 None
A0A2N3ZEH1 7-175 None
A0A2F0ANN3 139-294 None
A0A6C0LHY4 1-176 None
A0A4Q3V5J5 2-166 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.