DPCstruct | MC54344

Metacluster Properties and Pfam Annotations

Number of structural domains785
Mean domain length (aa)192 ± 50 aa
Standard deviation of domain lengths49.78
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score80.20
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)16.00
Pfam Score85.40
Assigned Pfam label(s) CL0063- CL0479- CL0123- PF13224- CL0248

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376ZVB3 44-210 NAITLPVCGRDVKFTLEVLRGDSVEKTSRVWSGNERDQELLTEDALDDLIPSFLLTGQQTPAFGRRVSGVIEIADGSRRRKAAALTE…
A0A7V1Q0T3 84-280 SVQVPHADGEPTAPTIIAIPVGSIIPNRNQPRKVFEDGSLRSLAESIRADGVMQPILVRPGSGSGSTGGRYELIAGERRWRAAKIAG…
A0A7W5HUS1 2-206 None
A0A7M7N1A7 51-305 None
A0A7M7HL81 130-391 None
A0A448EH90 4-229 None
A0A843FH83 5-178 None
H9UIK2 23-275 None
A0A2W7PNM5 3-154 None
I0X6M5 26-208 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.