DPCstruct | MC54250

Metacluster Properties and Pfam Annotations

Number of structural domains83
Mean domain length (aa)189 ± 40 aa
Standard deviation of domain lengths40.07
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score84.07
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)23.46
Pfam Score88.19
Assigned Pfam label(s) CL0123- PF20772- PF01709- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2N6A8I0 18-168 YEGIGPASSQYVVKAITDNKNRSASNIRHIFSKHGGSLASVMWNFEQKGVIRILKEKLPVLNEDQELELIELGAEDIQKEDEGYTII…
A0A7J5YXN7 61-255 HNKWSKVKHIKGPKDAARCKMFMKFALLIKLASKPGSQLTYEVRGPGGCMLLIEALTDNRTGTNHEIKRLLQRTGMISDGVRHNFIR…
A0A7R9A3Y1 168-383 None
A0A066VMP1 1-348 None
A0A449BKQ1 210-415 None
A0A1X6PFU6 105-324 None
A0A2H0TRA2 2-106 None
A0A1R3IVR8 436-663 None
A0A2C9JLT4 32-233 None
A0A1A9ZXV5 222-435 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.