DPCstruct | MC54169

Metacluster Properties and Pfam Annotations

Number of structural domains402
Mean domain length (aa)159 ± 29 aa
Standard deviation of domain lengths28.80
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score83.02
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)18.11
Pfam Score99.38
Assigned Pfam label(s) CL0020- CL0214- CL0280

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q6L282 3-123 YIIDGSNVAFGSGRPLAENISNMIRYLKKHGIENIIVICDASLRYKIIDKDHFENLVNLNIIKIAPAGTSADEFIIEYAKKNDAMII…
A0A178V2R5 10-161 YEAILDGANIGLYQQNFADGGFSLPQLEAVVKELYNKSGSKKQPLILLHKKRVNALLENPNHRNLVEEWINNNVLYATPPGSNDDWY…
A0A7S4L3L8 262-458 None
A0A6V7WAF6 26-177 None
Q7XK95 179-337 None
M4DAR2 836-996 None
A0A0M3IGL5 1-185 None
I3T310 141-305 None
A0A1V9Z6K8 3-169 None
A0A6L6C6B4 3-147 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.